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Ultraconserved Human DNA Element 80% Similar To Coelacanth Element





http://www.nature.com/news/2007/070903/full/449010b.html
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Only a single ultraconserved element has so far revealed its origins. By scanning genome data, Haussler's group found that one human ultraconserved element is 80% similar to a piece of DNA found in a 400-million-year-old class of ancient fish that includes the coelacanth. The element had been shuttled into the fish genome by a genetic invader called a retroposon, but mammals have now co-opted it to boost expression of a brain-development gene called ISL1.
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